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中文
将含有R278H变异（CGC替换为CAT）和一个敲除型诺卡因抗性（NeoR）基因的靶向载体插入到该位点。之后，通过Cre介导的重组手段去除了Neo。对胸腺细胞的总提取物进行的 Western-blot 检测显示，突变蛋白的表达水平略低于野生型。(来源：J:157574)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
