P110*转基因为5'至3'设计,包含一个splice接受器、一个由loxP标记的Neo-STOP cassette、P110*(一种激活形式的 mouse P110alpha(Pik3ca,磷脂酰肌醇3-激酶催化亚基)的cDNA序列、FRT标记的内质网导入增强绿色荧光蛋白 cassette(IRES-EGFP)以及牛的polyadenylation信号的序列。这个转基因为插入了Gt(ROSA)26Sor基因座的1号和2号外显子之间。(来源:J:157297)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Targeted
插入
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30

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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