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中文
在cre重组酶存在的情况下，通过删除22号和23号外显子，使得在C-末端产生提前终止。在23号内含子中插入了Neo cassette和第三个loxP位点。随后，通过cre介导的重组，去除了22号、23号外显子以及Neo cassette。通过western blot和免疫组化确认了大脑中无蛋白质表达。(来源：J:156578)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
