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中文
将人源单克隆抗体2F5定向靶向J区，去除J1到J4区域，生成人/小鼠嵌合抗体2F5。通过Cre介导的重组，去除了用于ES细胞选择的floxed neo cassette。2F5抗体是一种多反应和广谱中和抗体，能保护机体对抗猴免疫缺陷病毒(Simian HIV)的挑战。(来源：J:155798)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
