这个转基因包含了mouse Lfng基因的285bp B-block/block 3增强子的重复拷贝,β珠蛋白基底启动子,编码带有C端FLAG标签的鸡LFNG开放阅读框,以及SV40的3' UTR和polyadenylation信号。Lfng的B-block增强子在前体体节边缘邻近的颅顶体节中驱动表达。共产生了13个品系,该品系在颅顶条带中表达转基因,而在尾侧前体体节中的表达非常弱。(来源:J:155378)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(CBA x C57BL/6J)
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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