在exon 7中产生了一个突变,导致第629位的精氨酸被天冬氨酸替换(N629D)。同时,一个由floxed polII驱动的诺卡因筛选 cassette被插入到了intron 7。为了去除诺卡因选择性标记,这些小鼠与Meox2小鼠进行了杂交。(来源:J:155273)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
6
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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