这种突变等位基因保留了基因的5'端,通过前20个碱基对的exon 2编码蛋白质的第一个锌指。lacZ-PGK-neo cassette取代了exon2剩下的3'部分,包括内含子2和exon3,以及第二个和第三个锌指编码序列。RNA测序和E10.5胚胎的原位杂交都没有检测到转录本。(来源:J:155855)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
--
1
4
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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