这个转基因是通过将两个构建体,来源于能针对Kd54-68/I-Ab表位反应的CD4+ T细胞克隆,共同注射产生的。Tcra构建使用V alpha 1.1和J alpha 33,而Tcrb构建使用V beta 8.3(当前符号Trbv13-1)和J beta 1.4。两者都受到人类CD2启动子的调控。(参考文献:J:155849)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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20

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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