在内皮2染色体上插入了带有FRT标签的PGK-neo cassette,并在exon 2前方额外插入了一个loxP位点。目标区域,包括exon 2,大小为1.7kb。通过与携带Tg(ACTFLPe)9205Dym转基因的 mice杂交,FRT标签的PGK-neo cassette会被剔除。(来源:J:155250)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入
--
1
5
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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