插入了Velocigene cassette ZEN-Ub1导致染色体4(GRCm39构建)在5,674,0033-5,674,1353位点间形成了1,321bp的缺失。免疫组化(IHC)和 Western blot 检测在成年纯合突变小鼠的睾丸中证实了蛋白表达的缺失。(来源:J:136110, J:334022)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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