插入了Velocigene cassette ZEN-Ub1导致染色体4(GRCm39构建)在5,674,0033-5,674,1353位点间形成了1,321bp的缺失。免疫组化(IHC)和 Western blot 检测在成年纯合突变小鼠的睾丸中证实了蛋白表达的缺失。(来源:J:136110, J:334022)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count