这个靶向载体包含了一个cre/ERT2 cassette,它插入了Id2基因起始密码子位置,替换掉了大部分exon 1,但保留了最后25个核苷酸。cre cassette后面跟着一个frt-PGK-neo-frt cassette,这个序列在通过flp介导的去失后,在传代到生殖细胞时会被移除。(来源:J:154450)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv
Targeted
插入,基因内删除
--
1
--
27

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部