这个靶向构建包含一个CMV启动子,接着是LoxP66位点,一段编码反义小鼠Bmi1的cDNA,一个插入序列(IRES),一个eGFP插件盒,然后是LoxP71,后面跟着一个PGK启动子和neo cassette的neo标记。Cre表达能驱动反义Bmi1的反转。(来源:J:187257)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S4/SvJae
Targeted
插入
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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