在exon 2的上游插入了一个F3型的puro cassette带有5'的loxP位点,同时在exon 3的下游插入了一个frt型的neo cassette带有3'的loxP位点。短暂的flp表达会去除这两个选择 cassette,使得exons 2和3被标记为可删除。来源:(J:154651)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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