这个转基因包含了人类CYP2J2的cDNA,被克隆到了一个包含小鼠α-MHC启动子和人类生长激素内含子以及polyA序列的载体中,目的是驱动心肌细胞特异性表达这个转基因。共产生了6个转基因纯合品系,其中Tr2、Tr3、Tr5和Tr7这4个品系在心脏中显示出了丰富的转基因表达。(来源:J:101489)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NTac
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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