这个转基因载体包含了Cre重组酶的编码序列,后面跟着一个polyadenylation信号,用于在重组酶基因的起始转录密码子(ATG)处立即终止融合转录本。它被插入到小鼠基因组的细菌人工染色体(BAC)RP23-281A14中,通过利用鼠基因的调控序列驱动重组酶的表达。(来源:J:100256, J:145110)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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插入
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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