这条转基因大基因线包含了App的细胞内域和鼠Apbb1,两者都是由小鼠Camk2a启动子驱动,以在大脑前部和海马体中表达。共创造了四条线(仅标记为12和25),它们都表达这两种cDNA。第25号线被选为代表性线路。(来源:J:102815)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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插入
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2
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6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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