在exon 2的上游插入了loxP位点,接着在exon 5的3'端插入了带有loxP位点的frt-flanked neo cassette。通过小鼠的生殖细胞,使用flp介导的重组去除了neo cassette,使得exons 2到5都被留下了loxP标记。(来源:J:153555)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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