在exon 10的上游插入了loxP位点,通过同源重组,将一个含floxed neo cassette的片段插入到exon 12的下游。随后,通过Cre介导的重组,删除了neo cassette,使得exons 10至12区域被标记为可删除的。(来源:J:115188)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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