人类βactin(ACTB)启动子驱动表达Type IV Abl1的cDNA转录本。其中,一个导致K290R替换的点突变发生在酪氨酸激酶域和ATP结合域。载体被导入B6CBAF2胚胎中。(来源:J:34643)
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The human beta actin (ACTB) promoter drives expression of the Type IV Abl1 cDNA transcript. A point mutation causing a K290R substitution in the tyrosine kinase domain ATP binding domain. The vector was introduced to B6CBAF2 embryos. (J:34643)