使用细菌人工染色体(BAC)文库,获得了一个包含完整小鼠Trp53(转录因子53,也称为转化相关蛋白53)基因的130kb BAC,它在"自然基因组背景"中。Trp53基因位于该染色体的末端,而BAC的另一端位于Dnahc2基因的中间。这条线携带着这个转录因子的单拷贝基因。 (Source: BAC library was used to isolate a 130kb BAC containing the entire mouse Trp53 gene in its native genomic context, with one copy integrated in the Dnahc2 gene region.)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA)F2
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1
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15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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