A 3kb genomic fragment containing a truncated Pcp2 enhancer and gene drives cre/ERT2 followed by an IRES-ALPP (human placental alkaline phosphatase) sequence. The construct was injected into FVB/N oocytes and four founders were obtained. The line displaying the strongest expression in embryonic Purkinje cell (PC) clusters and adult medial-lateral PC stripes was chosen for further analysis. (J:152951)