从3号外显子到6号外显子的部分被替换成lacZ/neo载体。通过脑组织提取物的 Western blot 分析,证实了没有蛋白质表达(来源:J:152919)
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Exons 3 through 6 were replaced with a lacZ/neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:152919)