germ line(生殖细胞)通过Cre介导的重组移除了从2到4号的外显子以及neo cassette, 蛋白质表达的缺失通过在胚胎成纤维细胞提取物中进行 Western blot 分析得到了确认(来源:J:152821)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count