大部分exon 11和部分intron 11被一个floxed neo cassette替换了,通过脑组织的 Western blot 分析确认了没有蛋白表达(来源:J:152575)
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Most of exon 11 and part of intron 11 were replaced with a floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:152575)