从27号外显子到28号外显子的基因组序列被替换成了一个带有floxed neo cassette的元件。蛋白表达缺失通过在前额叶和海马的提取物中进行 Western blot 分析得到了确认(来源:J:152011)
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The genomic sequence from exon 27 through exon 28 was replaced with a floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on frontal cortex and hippocampus extracts. (J:152011)