Pik3cb^tm1.1Ehi

Exon 5 was replaced with one in which a point mutation results in an amino acid substitution of arginine for lysine at position 805 (K805R). A floxed neo cassette was used for selection purposes and removed by germ line, cre-mediated recombination. The predicted protein is expected to be a kinase dead version. (J:152332)