从BAC克隆519E21中分离出了同源臂。在第3个内含子中插入了frt介导的PGKneo cassette,同时在内含子2和4处插入了loxP位点。通过Flp介导的重组酶,正确靶向的ES细胞中去除了neo选择性 cassette。(来源:J:173366)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
插入
--
1
1
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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