第六和第七外显子被替换成一个带有floxed neo标签、floxed STOP以及人类RUNX1编码区域的元件。当通过Cre介导的重组去除floxed neo和STOP cassette时,产生了Etv6和人类RUNX1(或TEL-AML1)的融合产物。(来源:J:151639)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count