在第3和4外显子编码的开放阅读框被抗氨苄青霉素抗性基因座取代。通过Northern和Western分析在纯合巨噬细胞提取物中,确定了该基因座位表达的mRNA和蛋白质都被阻断了。(来源:J:151757)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Targeted
插入,基因内删除
--
1
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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