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在exon 10的位置替换了一段，其中用alanine替换掉了568和569位置上的保守的asp和glu氨基酸。接着插入了一个floxed neo cassette，并在生殖细胞中通过cre介导的重组移除了这一改变的exon 10。(来源：J:151700)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
