这个基因序列,从exon 2的起始密码子到exon 6,被替换了为带有NLS-lacZ和floxed neo元件的序列。随后,neo元件通过生殖细胞的Cre介导重组被去除了,因此这个等位基因丧失了整个编码区域。(来源:J:151626)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入,基因内删除
--
1
4
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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