Srr^rgsc1872

A T to A transversion was induced at the start of exon 9 resulting in a nonsense mutation (Tyr269Stop). Western blot analysis indicated absence of protein expression in the brains of homozygous mice. D-serine production assays indicated absence of protein activity in preparations from whole brain, hippocampus, and frontal cortex from homozygous mice. (J:151337)