ENU会导致种子区域的一个A变T转换,导致转录失稳和翻译抑制。在Akr1b10的第五外显子检测到一个额外的变异(C变T),但这个改变不影响密码子,不被认为导致该突变关联的表型。(来源:J:151354)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C3HeB/FeJ
Chemically induced
单点
半显性
--
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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