C. elegans的fat-1基因被修改以优化针对哺乳动物细胞的密码使用,并在小鼠中通过鸡β-actin启动子的控制下表达(这使得转录基因能在小鼠中以高水平和广谱的方式得到表达)。(来源:J:88166)
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The C. elegans fat-1 gene was modified to optimize codon usage for mammalian cells and was expressed in mice under the control of a chicken beta-actin promoter (which allows high-level and broad expression of the transgene in mice). (J:88166)