Grm5^tm1.1Kksz

The open reading frame was replaced with one containing two point mutations (TTC to CGC) in exon 8. These mutations result in an amino acid substitution of arginine for phenylalanine at position 1128 (F1128R). An upstream floxed neo was removed by germ line, cre mediated recombination. This mutation is expected to reduce Homer binding. (J:151084)