在内皮2号 intron插入了一个基因陷阱 cassette,导致该基因的正常转录受阻。对不同组织的细胞总提取物进行 Western blot 检测后,未发现可检测到的编码蛋白。(来源:J:233782)
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A gene trap cassette inserted into intron 2, disrupting normal transcription of the gene. Western blot on whole cell lysates of various tissues showed that no detectable encoded protein was present. (J:233782)