Tmem41b^{Gt(OST208407)Lex}

将一个 lentiviral 基因捕获载体插入了 Tmem41b（Stasimon）基因的第一个内含子。RT-qPCR 检测显示，杂合子突变胚胎中 mRNA水平大约减少了50%，而纯合子突变胚胎在E8.5时完全没有 mRNA表达。 (Source: The lentiviral gene trap vector was inserted into the intron 1 of Tmem41b (Stasimon), and RT-qPCR showed a ~50% decrease in mRNA levels in heterozygous mutants compared to controls, with no mRNA expression detected in homozygous mutants at E8.5.)