这个基因陷阱载体pGT2Lxf插入了基因sqRT-PCR分析显示在一些E10.5的纯合突变胚胎中表达水平较低,这表明这是一个功能减弱的等位基因。 (Source: The gene trap vector pGT2Lxf was inserted into intron 1 of the gene, and sqRT-PCR analysis indicated low expression in certain E10.5 homozygous mutant embryos, suggesting a hypomorphic allele.)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
基因捕获载体的插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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