这个基因陷阱载体pGT2Lxf插入了基因sqRT-PCR分析显示在一些E10.5的纯合突变胚胎中表达水平较低,这表明这是一个功能减弱的等位基因。 (Source: The gene trap vector pGT2Lxf was inserted into intron 1 of the gene, and sqRT-PCR analysis indicated low expression in certain E10.5 homozygous mutant embryos, suggesting a hypomorphic allele.)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count