一种基因陷阱载体插入到了内皮1号 intron。定量RT-PCR和 Western blot 分析显示,杂合突变小鼠脾组织中 mRNA 和蛋白质水平显著降低。(来源:J:226586)
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A gene trap vector inserted into intron 1. Quantitative RT-PCR and Western blot analysis revealed significantly reduced mRNA and protein levels in spleen tissue from heterozygous mutant mice. (J:226586)