将基因陷阱 cassette 插入到内皮2号染色体。在E10.5时观察到了广泛分布的lacZ表达。免疫印迹分析确认了纯合小鼠多种组织中无表达。 (Gene trap cassette inserted into intron 2. LacZ expression is widespread at E10.5. Immunoblot analysis confirmed the absence of expression in multiple tissues from homozygous mice, source: provided information)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count