这个基因陷阱载体被插入到了第7外显子下游。通过在纤维细胞和脑组织的 Western blot 分析,证实了没有蛋白质表达。 (Gene trap vector inserted downstream of exon 7. Protein expression absence confirmed by Western blot on fibroblast and brain extracts, source: no additional information provided)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count