一种包含β-geo报告基因的基因陷阱载体,它被插入在1号和2号外显子之间,导致了功能丧失突变。RT-PCR证实了E10同源突变胚胎中mRNA表达的缺失。通过免疫印迹分析,在E11.5突变胚胎的分离出的线粒体中未检测到编码蛋白。(来源:J:261656)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Gene trapped
基因捕获载体的插入
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部