Tmem184b^{Gt(IST10294F4)Tigm}

这个基因被一个基因陷阱 cassette 插入到了第一个和第二个外显子之间，导致其功能受损。定量 PCR 分析显示，纯合突变小鼠成年脑组织中该基因的 RNA 表达减少了大约 20 倍。 (Source: Gene disruption by a gene-trap cassette between the first and second exons, with RNA expression reduction quantified in adult brain tissue from homozygous mutant mice)