通过基因座重叠和链方向确定的被困基因关联。逆转录病毒基因陷阱载体插入了内2号 intron。这种插入通过在内2号 intron内插入一个强的剪接接受体位点,导致产生一个与β-geo报告基因连接的剪切异常的mRNA。RT-PCR确认皮肤、肠道、肾脏和肺部均无mRNA, Western blot分析也证实了无蛋白存在。(来源:J:214122)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Gene trapped
基因捕获载体的插入
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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