这个基因被一个基因陷阱载体打断,该载体替换了2-6号外显子。大脑组织匀浆的 Western blot 分析显示,来自这个等位基因的两种特有异构体没有表达。(来源:J:238439)
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The gene is disrupted by a gene trap vector that replaced exons 2-6. Western blot analysis of brain lysate shows the lack of expression of the two brain-specific isoforms from this allele. (J:238439)