大部分开放阅读框被替换为一个包含EGFP、cre和frt flanked neo的盒式元件,它以非起始密码子位置插入。这个插入的盒式元件取代了原有蛋白质321个氨基酸中20到315位的序列。通过小鼠的生殖细胞,flp介导的重组会去除neo盒式元件。(来源:J:150802)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入,基因内删除
--
1
--
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部