Et(icre)754Rdav

An enhancer trap transgenic approach was used to generate these mice. The TK-bgi-icre-bGHpA transgene was designed with the thymidine kinase minimal (TK) promoter minimal promoter driving a codon-improved cre recombinase sequence (icre). A beta globin intron separates the promoter from the cre gene and the bovine growth hormone polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 754 was established on a C57BL/6J genetic background. (J:150856)