这段文字翻译成中文是: 从exon 1到部分内含子2被替换为C57BL/6小鼠相应的序列。尽管创造这个等位基因的ES细胞来自(129S1/SvImJ x NOD/ShiLtJ)F1杂交,但靶向事件定位在NOD基因上。插入序列下游的删除型neo cassette通过ES细胞中短暂的Cre表达被移除。(来源:J:150823)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S1/SvImJ x NOD/ShiLtJ)F1
Targeted
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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