在1和2号外显子被替换成一个带有floxed Neo cassette的序列。随后,通过短暂表达Cre重组酶,Neo cassette被移除。对纯合脾细胞或Th17细胞的免疫印迹分析中未检测到蛋白质产品。(来源:J:150643)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入,基因内删除
--
1
--
32

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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