将包含人类配对样同源盒2(human, PITX2A)异构体的转录本,由小鼠角蛋白(Kera)驱动的调控序列,以及兔β-球蛋白的polyA信号序列的转基因构建,注入了CBAB6F2雌鼠的受精卵中。获得了多个克隆。在B线中,观察到12B3染色体上有多个拷贝整合。A和B线表型一致。(来源:J:93634)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(CBA x C57BL/6)F2
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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